Beilstein J. Org. Chem.2021,17, 1712–1724, doi:10.3762/bjoc.17.119
Information File 3 (Table S5).
A systemsglycobiology framework to link multi-OMICs data. a) Cell signaling proceeds to trigger TF activity. The binding of TFs to sites proximal to the TSS triggers glycogene expression. A complex set of reaction pathways then results in the synthesis of various carbohydrate
PDF
Graphical Abstract
Figure 1:
A systems glycobiology framework to link multi-OMICs data. a) Cell signaling proceeds to trigger TF...
Beilstein J. Org. Chem.2020,16, 2645–2662, doi:10.3762/bjoc.16.215
. Krambeck Kiyoko F. Aoki-Kinoshita Nathan E. Lewis See end of main text. 10.3762/bjoc.16.215 Abstract Systemsglycobiology aims to provide models and analysis tools that account for the biosynthesis, regulation, and interactions with glycoconjugates. To facilitate these methods, there is a need for a
compliance with FAIR standards. Here, we present Linear Code for Reaction Rules (LiCoRR), version 1.0, an unambiguous representation for describing glycosylation reactions in both literature and code.
Keywords: glycoinformatics; linear code; systemsglycobiology; Introduction
Glycans are predominantly
representations are not designed to be human-readable or included in the main text of a manuscript confining many design details to the supplement of a publication. As systemsglycobiology develops, there is a need to develop a standard nomenclature for unambiguous and readable reaction rules to facilitate
PDF
Graphical Abstract
Figure 1:
Common terminology and anatomy of a theoretical glycan, (KJ(IH)GF(D(E)(C)B)A. In this figure, we de...